The utility model discloses a guide bracket for a cryogenic vertical pipeline. wherein the heat insulation layer, the cold insulation layer and the steel hoop are sequentially arranged outside the copious cooling vertical pipeline from inside to outside. The steel hoop comprises an upper steel hoop body and a lower steel hoop body which are detachably connected, a guide assembly is arranged outside the steel hoop body and comprises a rib plate connected with the steel hoop body and a guide plate connected with the rib plate in a T-shaped mode, and guide clamping blocks are symmetrically arranged at the two ends of the guide plate. The guide bracket for the cryogenic vertical pipeline provided by the utility model can accurately control the requirement of axial displacement of the cryogenicvertical pipeline.