The utility model relates to a multi-degree-of-freedom adjusting device and a spraying system, the multi-degree-of-freedom adjusting device comprises a mounting mechanism and a rotating frame mountingseat, and the mounting mechanism comprises a driving cylinder, a positioning control valve, a driving cylinder fixing seat and a connecting part; the end of a piston rod of the driving cylinder is fixedly connected with a to-be-adjusted component, and the driving cylinder fixing base is arranged on the connecting component in a sliding mode and can slide relative to the connecting component in the extending or shortening direction of the piston rod. The rotating frame mounting base comprises a connecting plate and a plurality of fixing blocks, the connecting plate is slidably connected with the connecting part, and the connecting plate can slide relative to the connecting part; the plurality of fixing blocks are fixedly connected with the connecting plate and are fixed on the mounting part. The spraying system comprises a powder spraying chamber, spraying equipment and a multi-degree-of-freedom adjusting device. According to the spraying system, the distance between the powder spraying chamber and the pipe wall of the pipeline is accurately positioned, and the uniformity of an FBE coating during pipeline anticorrosion joint coating construction is guaranteed.