The utility model discloses lead screw cleaning equipment for an upper support and a lower support. Including an intermediate shaft, the intermediate shaft is driven by a motor to rotate; the end partof the intermediate shaft is connected with a three-jaw chuck; a cutter is arranged on the three-jaw chuck; wherein the cutter is of a cylindrical structure, the inner wall of the cutter is matched with threads on the outer wall of the lead screw, the two sliding rails are symmetrically arranged on the two sides of the three-jaw chuck, a sliding block is arranged between the two sliding rails, atray clamp used for fixing the cutter is arranged on the sliding block, and the sliding block is driven by a motor to move back and forth on the sliding rails. The problems of low working efficiency and poor cleaning quality caused by manual cleaning of the upper support lead screw and the lower support lead screw in the prior art are solved.