The utility model discloses a production system of hexamethylenediamine. The hexamethylenediamine production system comprises a premixer, a reactor, a gas phase condenser, a hydrogen compressor, a catalyst recovery tank, a material buffer tank, a filter, a dealcoholization tower preheater, a dealcoholization tower, a phase separator, an intermediate tank, a dehydration tower, a first heavy component removal tower, a first light component removal tower, a second light component removal tower, a finished product tower, a second heavy component removal tower and a third heavy component removal tower, the method comprises the following steps: mixing raw materials in a premixer, feeding into a reactor, and introducing hydrogen into the reactor for reaction; filtering the material obtained by the reactor through a filter, and feeding into a dealcoholization tower preheater; materials enter a dealcoholization tower after passing through a dealcoholization tower preheater, the materials are fed into a phase separator through the dealcoholization tower preheater after ethanol is removed from the materials in the dealcoholization tower, in the phase separator, the materials are separated from a sodium hydroxide aqueous solution, and the separated materials are subjected to dehydration and a series of heavy component removal and light component removal treatment to obtain finished products.