An offshore large-span ground anchor type suspension cable and cable-stayed cooperative system bridge structure relates to the field of bridge engineering and comprises a supporting structure which comprises anchor ingots and a main tower, and the main tower is located between the two anchor ingots; the separated steel box girders are respectively supported on the anchors at the two ends and the main tower along the bridge direction; the two main cables are respectively connected with the anchors at the two ends and the main tower; the stay cable is of a spatial four-cable-plane structure, andthe two ends of the stay cable are tensioned on the main tower and the separated steel box girder respectively; wherein a suspender is connected between the main cable and the side surface of the separated steel box girder, the separated steel box girder comprises two cross beams and two girder plates, the two girder plates are arranged on the two sides of the main tower in parallel along the bridge direction, the cross beams are perpendicular to the girder plates and are discontinuously arranged between the two girder plates, and the upper surfaces of the girder plates are of horizontal plane and lower surface streamline curved surface structures. According to the utility model, the wind-resistant stability of the main structure is greatly improved; the spatial four-cable-plane structureobviously improves transverse stress and effectively reduces the height of the cross beam and the engineering quantity of the cross beam.