The utility model relates to a toothbrush with a transmission holder, particularly an electric health care toothbrush which comprises a brush head and a brush holder. The utility model is characterized in that one end of the brush holder is fixedly provided with the brush head, a motor transmission device by which the brush holder is driven to be rotated is arranged on the other end, the brush head is formed in a way that the brush bristles are fixed on a brush column, and the brush head and the brush holder can be formed into a whole. The electric health care toothbrush aims to popularize and apply a toothbrush which prevents dental disease, and enables people to adopt the correct tooth brushing method that teeth are vertically brushed up and down, and oral cavity residue on tooth roots and in tooth gaps is effectively removed. The utility model has the advantages of convenient operation, labor saving, time saving and low cost.