A high efficiency solid-liquid separation device comprises a mix reaction section (9), a mud-slag concentrating section (10), a separating section (11), and a filtration section (12). The utility model takes the shape of a cylinder, the mix reaction section (9), which is arranged on the bottom of the cylinder, takes the shape of a truncated cone, is coaxial with the outer cylinder, and has a same bottom face with the outer cylinder. The loop room formed by the truncated and the outer cylinder is the mud-slag concentrating section (10), the separating section (11) is arranged on the middle portion of the cylinder, the filtration section (12) is arranged on the top portion of the cylinder. The mix reaction section (9), the mud-slag concentrating section (10), the separating section (11), and the filtration section (12) have the same central axes. The utility model has the advantages of reasonable design, compact structure, large disposed water, and good quality of charged water.