The utility model discloses a fluorescence antifake material sheet, belonging to the field of the antifake material sheet. The utility model mainly solves the problem of material sheet antifake. An antifake mark (3) which can be reflected only under the radiation of ultraviolet light and whose position or shape can be unfixed are arranged on the surface of a material sheet body(1). The manufacture method of the fluorescence antifake material sheet is that the fluorescence antifake mark (3) is firstly produced on the surface of a special organic thin film, after the fluorescence antifake mark (3) is dried and formed, the fluorescence antifake mark (3) is under standby condition, and when the material sheet body(1) is produced by pressing, heating, maturing and shaping, the organic thin film with the fluorescence antifake mark (3) is laid up on the top surface or the relevant position of the bottom surface of the material sheet body(1). After the material sheet is shaped, the fluorescence antifake mark (3) is on the surface of the material sheet body (1), firmly and integrally combined with the material sheet body(1) together, and a layer of firm protective layer (2) is formed on the surface of the fluorescence antifake mark (3). The utility model has the benefits of that under the radiation of ultraviolet light, the fluorescence antifake mark (3) can be reflected, therefore the identification problem of the true and fake material sheets can be reliably and effectively solved, and the utility model is of simple producing and convenient identification and application, and the fluorescence antifake material sheet is especially suitable for a multi-layer high-grade material sheet which is made of animal, plant and organic synthetic materials in a mixed way.