发明公开
EP0013817A1 1-Imidazol-2-ylidene-3-thienyl-urea derivatives, processes therefor, and pharmaceutical compositions
失效
1-咪唑-2-亚基-3-噻吩基 - 恶唑烷酮，Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen。
- 专利标题： 1-Imidazol-2-ylidene-3-thienyl-urea derivatives, processes therefor, and pharmaceutical compositions
- 专利标题（中）： 1-咪唑-2-亚基-3-噻吩基 - 恶唑烷酮，Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen。
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申请号： EP79302921.6申请日： 1979-12-17
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公开(公告)号： EP0013817A1公开(公告)日： 1980-08-06
- 发明人: Bare, Thomas Michael
- 申请人： ICI AMERICAS INC.
- 申请人地址： Concord Pike & New Murphy Road Wilmington Delaware 19897 US
- 专利权人： ICI AMERICAS INC.
- 当前专利权人： ICI AMERICAS INC.
- 当前专利权人地址： Concord Pike & New Murphy Road Wilmington Delaware 19897 US
- 代理机构： Allerton, Roy
- 优先权： US4675 19790119
- 主分类号： C07D409/12
- IPC分类号： C07D409/12 ; A61K31/415
摘要：
Compounds of the formula:
wherein R stands for a lower alkyl radical and Z stands for a pyridyl, thienyl or furyl radical, any of which may optionally be substituted with 1 to 3 defined substituents, and salts thereof. Two processes for the manufacture of said compounds. Pharmaceutical compositions comprising any one of said compounds together with a pharmaceutically-acceptable diluent or carrier. The compounds exhibit anxiolytic activity, and some of them block acid secretions.
wherein R stands for a lower alkyl radical and Z stands for a pyridyl, thienyl or furyl radical, any of which may optionally be substituted with 1 to 3 defined substituents, and salts thereof. Two processes for the manufacture of said compounds. Pharmaceutical compositions comprising any one of said compounds together with a pharmaceutically-acceptable diluent or carrier. The compounds exhibit anxiolytic activity, and some of them block acid secretions.
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