发明公开
EP0031567A2 Tetrapeptidesemicarbazide derivatives and their production and use
失效
Tetrapeptidsemicarbazid衍生物及其制备方法和用途。
- 专利标题： Tetrapeptidesemicarbazide derivatives and their production and use
- 专利标题（中）： Tetrapeptidsemicarbazid衍生物及其制备方法和用途。
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申请号： EP80108083.9申请日： 1980-12-20
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公开(公告)号： EP0031567A2公开(公告)日： 1981-07-08
- 发明人: Masahiko, Fujino , Mitsuhiro, Wakumasu , Kiyohisa, Kawai
- 申请人： Takeda Chemical Industries, Ltd.
- 申请人地址： 1-1, Doshomachi 4-chome Chuo-ku, Osaka JP
- 专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人地址： 1-1, Doshomachi 4-chome Chuo-ku, Osaka JP
- 代理机构： von Kreisler, Alek, Dipl.-Chem.
- 优先权： JP173608/79 19791227
- 主分类号： C07C103/52
- IPC分类号： C07C103/52 ; A61K37/02 ; C07C133/00 ; C07C159/00
摘要：
Novel tetrapeptidesemicarbazide derivatives, inclusive of a pharmacologically acceptable salt thereof, which has the general formula (I):
wherein R 1 is hydrogen or lower alkyl; R 2 is hydrogen or a D-α-amino acid side chain; R 3 is hydrogen or lower alkyl; X is oxygen or sulfur, are useful as analgesics.
wherein R 1 is hydrogen or lower alkyl; R 2 is hydrogen or a D-α-amino acid side chain; R 3 is hydrogen or lower alkyl; X is oxygen or sulfur, are useful as analgesics.
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