发明公开
- 专利标题: Phosphinylalkanoyl substituted imino acids
- 专利标题(中): 氧膦取代的亚氨基酸。
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申请号: EP83104912.7申请日: 1983-05-18
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公开(公告)号: EP0094687A1公开(公告)日: 1983-11-23
- 发明人: Karanewsky, Donald S. , Petrillo, Edward W., Jr.
- 申请人: E.R. Squibb & Sons, Inc.
- 申请人地址: Lawrenceville-Princeton Road Princeton, N.J. 08540-4000 US
- 专利权人: E.R. Squibb & Sons, Inc.
- 当前专利权人: E.R. Squibb & Sons, Inc.
- 当前专利权人地址: Lawrenceville-Princeton Road Princeton, N.J. 08540-4000 US
- 代理机构: VOSSIUS & PARTNER
- 优先权: US379678 19820519
- 主分类号: C07F9/65
- IPC分类号: C07F9/65 ; A61K31/675
摘要:
Phosphinylakanoyl imino acids of the formula
wherein X is tetrahydroisoquinoline carboxylic acid, dihyd- roindole or dihydroisoindole carboxylic acid are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.
wherein X is tetrahydroisoquinoline carboxylic acid, dihyd- roindole or dihydroisoindole carboxylic acid are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.
公开/授权文献
- EP0094687B1 Phosphinylalkanoyl substituted imino acids 公开/授权日:1986-09-10
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