发明公开
EP0118676A1 D-Xylopyranoside series compounds and therapeutical compositions containing same
失效
D-吡喃木糖苷系列化合物和含有它们的治疗组合物
- 专利标题: D-Xylopyranoside series compounds and therapeutical compositions containing same
- 专利标题(中): D-吡喃木糖苷系列化合物和含有它们的治疗组合物
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申请号: EP84100499.7申请日: 1981-12-07
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公开(公告)号: EP0118676A1公开(公告)日: 1984-09-19
- 发明人: Noyori, Ryoji , Suzuki, Sakaru , Okayama, Minoru , Sakurai, Katukiyo , Kamohara, Shigeyoshi , Ueno, Yoshio
- 申请人: Seikagaku Kogyo Co. Ltd.
- 申请人地址: 9-8, Nihonbashi-honcho 2-chome Chuo-ku Tokyo JP
- 专利权人: Seikagaku Kogyo Co. Ltd.
- 当前专利权人: Seikagaku Kogyo Co. Ltd.
- 当前专利权人地址: 9-8, Nihonbashi-honcho 2-chome Chuo-ku Tokyo JP
- 代理机构: Hansen, Bernd, Dr. Dipl.-Chem.
- 优先权: JP172625/80 19801209; JP65226/81 19810501; JP65227/81 19810501; JP144001/81 19810914; JP175772/81 19811104
- 主分类号: C07H15/14
- IPC分类号: C07H15/14 ; C07H15/18 ; A61K31/70
摘要:
Disclosed are D-xylopyranoside series compounds represented by the following general formula:
in which R 1 represents
wherein X represents a sulfur atom, Y represents a hydrogen, a lithium, a sodium, a potassium, a magnesium, a calcium or an aluminum atom; and p represents a valency of an atom represented by Y; -S-R 2 (R 2 represents a straight-chain alkyl group having from 9 to 25 carbon atoms or a branched alkyl group having from 4 to 25 carbon atoms, a straight-chain or a branched alkenyl group having from 3 to 25 carbon atoms, or a straight-chain or a branched alkynyl group having from 3 to 25 carbon atoms). In form of therapeutical compositions the compounds are effective against various diseases, including those caused by lipid deposition on the walls of blood vessels and cancer.
in which R 1 represents
wherein X represents a sulfur atom, Y represents a hydrogen, a lithium, a sodium, a potassium, a magnesium, a calcium or an aluminum atom; and p represents a valency of an atom represented by Y; -S-R 2 (R 2 represents a straight-chain alkyl group having from 9 to 25 carbon atoms or a branched alkyl group having from 4 to 25 carbon atoms, a straight-chain or a branched alkenyl group having from 3 to 25 carbon atoms, or a straight-chain or a branched alkynyl group having from 3 to 25 carbon atoms). In form of therapeutical compositions the compounds are effective against various diseases, including those caused by lipid deposition on the walls of blood vessels and cancer.
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