发明公开
EP0118875A1 6-(Hydroxyalkyl)-2-(heteroarylalkylthio)-penems, pharmaceutical compositions containing them, and processes for their preparation
失效
6-（羟烷基）-2-（heteroarylalkylthio）-Peneme，含有它们的它们的制备方法的药物组合物。
- 专利标题： 6-(Hydroxyalkyl)-2-(heteroarylalkylthio)-penems, pharmaceutical compositions containing them, and processes for their preparation
- 专利标题（中）： 6-（羟烷基）-2-（heteroarylalkylthio）-Peneme，含有它们的它们的制备方法的药物组合物。
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申请号： EP84102429.2申请日： 1984-03-07
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公开(公告)号： EP0118875A1公开(公告)日： 1984-09-19
- 发明人: Girijavallabhan, Viyyoor Moopil , Ganguly, Ashit Kumar , Pinto, Patrick Anthony , Versace, Richard William
- 申请人： SCHERING CORPORATION
- 申请人地址： 2000 Galloping Hill Road Kenilworth New Jersey 07033 US
- 专利权人： SCHERING CORPORATION
- 当前专利权人： SCHERING CORPORATION
- 当前专利权人地址： 2000 Galloping Hill Road Kenilworth New Jersey 07033 US
- 代理机构： Ritter, Stephen David
- 优先权： US475281 19830314; US564586 19831222
- 主分类号： C07D499/00
- IPC分类号： C07D499/00 ; A61K31/43
摘要：
Compounds of the general formula
In which G is hydroxyloweralkyl;
R 1 is chosen from various substituents;
n is 1 to 4;
Q is the group
in which X is =N- or
and R is chosen from various substituents; and their pharmaceutically acceptable salts and esters. Various processes for their preparation are disclosed. The compounds have antibacterial activity.
In which G is hydroxyloweralkyl;
R 1 is chosen from various substituents;
n is 1 to 4;
Q is the group
in which X is =N- or
and R is chosen from various substituents; and their pharmaceutically acceptable salts and esters. Various processes for their preparation are disclosed. The compounds have antibacterial activity.
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