发明公开
EP0126342A3 3-Alkyl-8-chloro-5,6-dihydrofuro-[3,2-f]-1,2-benzisoxazole-6-carboxylic acids
失效
3-氨基-8-氯代-5,6-二氢呋喃并[3,2-b] -1,2-苯并噻唑-6-羧酸
- 专利标题: 3-Alkyl-8-chloro-5,6-dihydrofuro-[3,2-f]-1,2-benzisoxazole-6-carboxylic acids
- 专利标题(中): 3-氨基-8-氯代-5,6-二氢呋喃并[3,2-b] -1,2-苯并噻唑-6-羧酸
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申请号: EP84104865申请日: 1984-05-02
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公开(公告)号: EP0126342A3公开(公告)日: 1987-11-04
- 发明人: Parks, James Arvil , Plattner, Jacob John
- 申请人: ABBOTT LABORATORIES
- 专利权人: ABBOTT LABORATORIES
- 当前专利权人: ABBOTT LABORATORIES
- 优先权: US494751 19830516
- 主分类号: C07D498/04
- IPC分类号: C07D498/04 ; A61K31/42 ; C07D307/00 ; C07D261/00
摘要:
Disclosed are compounds of the formula:
wherein X is hydrogen, loweralkyl, loweralkoxy or halo, Y is hydroxymethyl, carboxyl, carboxamido or carboloweralkoxy, and R is cyclohexyl, benzyl, norbornyl, loweralkyl, or a pharmaceutically acceptable salt thereof. The compounds are effective as diuretic agents.
wherein X is hydrogen, loweralkyl, loweralkoxy or halo, Y is hydroxymethyl, carboxyl, carboxamido or carboloweralkoxy, and R is cyclohexyl, benzyl, norbornyl, loweralkyl, or a pharmaceutically acceptable salt thereof. The compounds are effective as diuretic agents.
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