发明公开
EP0131174A1 Substituted phenylglycine derivatives of beta-lactam antibiotics
失效
的β-内酰胺抗生素取代的苯基甘氨酸衍生物。
- 专利标题： Substituted phenylglycine derivatives of beta-lactam antibiotics
- 专利标题（中）： 的β-内酰胺抗生素取代的苯基甘氨酸衍生物。
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申请号： EP84106915.6申请日： 1984-06-16
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公开(公告)号： EP0131174A1公开(公告)日： 1985-01-16
- 发明人: Burton, George , Best, Desmond John
- 申请人： BEECHAM GROUP PLC
- 申请人地址： Beecham House, Great West Road Brentford, Middlesex TW8 9BD GB
- 专利权人： BEECHAM GROUP PLC
- 当前专利权人： BEECHAM GROUP PLC
- 当前专利权人地址： Beecham House, Great West Road Brentford, Middlesex TW8 9BD GB
- 代理机构： Dayneswood, Trevor
- 优先权： GB8318374 19830707; GB8401443 19840119
- 主分类号： C07D499/68
- IPC分类号： C07D499/68 ; C07D501/20 ; C07D241/08 ; C07C101/72 ; C07C125/065 ; A61K31/43 ; A61K31/545
摘要：
A compound having the partial structure (I)
wherein R' and R 2 may be the same or different and each is hydrogen or a group -COR 5 or -CO-OR 5 wherein R 5 represents an optionally substituted hydrocarbon group; R 3 is halogen and R 4 is hydrogen, methoxy, hydroxymethyl or formamido.
These compounds are suitably bicyclic β-lactam antibiotics
wherein R' and R 2 may be the same or different and each is hydrogen or a group -COR 5 or -CO-OR 5 wherein R 5 represents an optionally substituted hydrocarbon group; R 3 is halogen and R 4 is hydrogen, methoxy, hydroxymethyl or formamido.
These compounds are suitably bicyclic β-lactam antibiotics
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