发明公开
EP0160036A4 NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA.
失效
新的合成方法用作非离子型造影射线照相。
- 专利标题： NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA.
- 专利标题（中）： 新的合成方法用作非离子型造影射线照相。
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申请号： EP84903867申请日： 1984-10-12
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公开(公告)号： EP0160036A4公开(公告)日： 1987-06-11
- 发明人: SOVAK MILOS , RANGANATHAN RAMACHANDRAN
- 申请人： BIOPHYSICA FOUNDATION
- 专利权人： BIOPHYSICA FOUNDATION
- 当前专利权人： BIOPHYSICA FOUNDATION
- 优先权： US54430883 1983-10-20
- 主分类号： C07C233/65
- IPC分类号： C07C233/65 ; A61K49/04 ; C07C67/00 ; C07C231/00 ; C07C231/02 ; C07C231/08 ; C07C233/00 ; C07C233/48 ; C07C237/30 ; C07C237/46 ; C07C102/00 ; C07C103/78
摘要：
Methods for substituting aromatic carboxylic acids and derivatives thereof and amino substituted aromatic carboxylic acids and derivatives thereof, by forming imides and imide-amides, respectively, by acylation with aliphatic carboxylic acids, substituting at least one nitrogen atom under mild basic conditions with an aliphatic compound having as alkylating agent a displaceable functionality and removing undesired acyl group, as appropriate.
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