发明公开
- 专利标题： Anticonvulsive compounds
- 专利标题（中）： 有毒化合物
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申请号： EP85303451申请日： 1985-05-16
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公开(公告)号： EP0162669A3公开(公告)日： 1986-11-20
- 发明人: Teranishi, Masayuki , Murakata, Chikara , Matsukuma, Ikuo , Shuto, Katsuichi , Ichikawa, Shunji
- 申请人： KYOWA HAKKO KOGYO CO., LTD.
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 优先权： JP9819384 19840516
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; C07D239/22
摘要：
For use an an anticonvulsive: dihydrouracil compounds of the formula
where one of A and B is
(where Y, Y 2 and Y 3 are each H, C 1 -C 4 straight- or branched-chain alkyl, halogen, nitro, amino. carboxyl, alkoxycarbonyl of 2-7 carbon atoms or -CF 3 ), naphthyl or diphenylmethyl and the other is H, C 1 -C 6 straight- or branched-chain alkyl, C 1 -C 6 alkenyl, cyclopentyl, cyclohexyl or
(where Z 1 , Z 2 and Z 3 are each H, C 1 -C 4 straight- or branched-chain alkyl, halogen or -CF 3 ); X is 0 or S; and R 1 , R 2 and R 3 are each H or C 1 -C 3 straight- or branched-chain alkyl.
where one of A and B is
(where Y, Y 2 and Y 3 are each H, C 1 -C 4 straight- or branched-chain alkyl, halogen, nitro, amino. carboxyl, alkoxycarbonyl of 2-7 carbon atoms or -CF 3 ), naphthyl or diphenylmethyl and the other is H, C 1 -C 6 straight- or branched-chain alkyl, C 1 -C 6 alkenyl, cyclopentyl, cyclohexyl or
(where Z 1 , Z 2 and Z 3 are each H, C 1 -C 4 straight- or branched-chain alkyl, halogen or -CF 3 ); X is 0 or S; and R 1 , R 2 and R 3 are each H or C 1 -C 3 straight- or branched-chain alkyl.
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