发明公开
- 专利标题： Substituted phenoxypropylaminoethoxyphenoxyacetamides
- 专利标题（中）： 取代的苯氧基丙烯酰胺
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申请号： EP85109984申请日： 1985-08-08
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公开(公告)号： EP0171760A3公开(公告)日： 1987-05-06
- 发明人: Duckworth, David Malcolm , Jennings, Leslie John Arthur
- 申请人： BEECHAM GROUP PLC
- 专利权人： BEECHAM GROUP PLC
- 当前专利权人： BEECHAM GROUP PLC
- 优先权： GB8420837 19840816
- 主分类号： C07C103/34
- IPC分类号： C07C103/34 ; A61K31/16
摘要：
Compounds of the general formula (I)
, or a pharmaceutically acceptable salt thereof, in which
R represents a hydroxy group or an in vivo hydrolysable ester thereof, R' represents a hydroxy group in the 2-, 3-, or 4-position, or an ester thereof, R 2 represents a hydrogen atom or a lower alkyl group, R 3 and R 4 , which may be the same or different, each represents a hydrogen atom; an alkyl radical; or an unsubstituted or substituted aryl, arylalkyl or diarylalkyl radical; or R 3 and R 4 , together with the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered saturated or unsaturated heterocyclic radical; a process for preparing such a compound, pharmaceutical compositions containing them; and their use in medicine.
, or a pharmaceutically acceptable salt thereof, in which
R represents a hydroxy group or an in vivo hydrolysable ester thereof, R' represents a hydroxy group in the 2-, 3-, or 4-position, or an ester thereof, R 2 represents a hydrogen atom or a lower alkyl group, R 3 and R 4 , which may be the same or different, each represents a hydrogen atom; an alkyl radical; or an unsubstituted or substituted aryl, arylalkyl or diarylalkyl radical; or R 3 and R 4 , together with the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered saturated or unsaturated heterocyclic radical; a process for preparing such a compound, pharmaceutical compositions containing them; and their use in medicine.
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