发明授权
- 专利标题: NMR CONTRAST AGENTS
- 专利标题(中): NMR对比剂
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申请号: EP85902602.3申请日: 1985-05-31
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公开(公告)号: EP0183760B1公开(公告)日: 1992-03-18
- 发明人: SADLER, Peter, John , HARDING, Charles, Thomas
- 申请人: GUERBET S.A.
- 申请人地址: 15, rue des Vanesses F-93430 Villepinte FR
- 专利权人: GUERBET S.A.
- 当前专利权人: GUERBET S.A.
- 当前专利权人地址: 15, rue des Vanesses F-93430 Villepinte FR
- 代理机构: Polus, Camille
- 优先权: GB8413849 19840531
- 国际公布: WO8505554 19851219
- 主分类号: A61K49/00
- IPC分类号: A61K49/00
摘要:
An agent for modifying H2O relaxation times in NMR diagnosis comprises a polysaccharide having chemically linked to it an organic complexant to which is complexed a paramagnetic metal ion. Polysaccharides include cellulose, starch, sepharose and dextran. Organic complexants include EDTA, DTPA and aminoethyl diphosphonate. A preferred metal ion is Gadolinium (III). The agents can be administered orally or parenterally.
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