发明公开
- 专利标题： N-Methylphenylserine alkyl ester derivatives and uses thereof
- 专利标题（中）： 衍生缬氨酸N-甲基苯基西兰和德安恩。
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申请号： EP86307456.3申请日： 1986-09-29
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公开(公告)号： EP0218440A2公开(公告)日： 1987-04-15
- 发明人: Umezawa, Hamao , Nagatsu, Toshiharu , Takeuchi, Tomio , Sasaki, Fujinori CO-OP Shincho No. 203 , Morishima, Hajime , Sawasaki, Yoshio , Takezawa, Hiroshi
- 申请人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI , BANYU PHARMACEUTICAL CO., LTD.
- 申请人地址： 14-23, Kami Ohsaki 3-chome Shinagawa-ku Tokyo JP
- 专利权人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI,BANYU PHARMACEUTICAL CO., LTD.
- 当前专利权人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI,BANYU PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 14-23, Kami Ohsaki 3-chome Shinagawa-ku Tokyo JP
- 代理机构： Moon, Donald Keith
- 优先权： JP214993/85 19850930
- 主分类号： C07C101/32
- IPC分类号： C07C101/32 ; A61K31/195 ; C07C101/72
摘要：
As new compounds N-methyl-3-(3,4-dihydroxyphenyl)serine alkyl esters. These are effective as a-adrenergic and β-adrenergic agenta to stimulate the a-adrenergic and β-adrenergic functions of the central nervous system of mammalian animals. Such compounds can be useful for therapeutic treatment of disorders as invoked by reduced biological activities or functions of the a-and/or β-adrenergic neurons. N-methyl-L-threo-3-(3,4-dihydroxyphenyl)serine (C 1 - Cs) alkyl esters are preferred amongst the new compounds of this invention.
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