发明公开
- 专利标题： Antihypercholesterolemic compounds
- 专利标题（中）： 抗高胆固醇血症Verbindungen。
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申请号： EP87303742.8申请日： 1987-04-28
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公开(公告)号： EP0245990A2公开(公告)日： 1987-11-19
- 发明人: Hoffman, William F. , Lee, Ta Jyh , Smith, Robert L. , Rooney, Clarence S.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Cole, William Gwyn
- 优先权： US859534 19860505
- 主分类号： C07D309/30
- IPC分类号： C07D309/30 ; C07C69/732 ; A61K31/35 ; A61K31/365 ; A61K31/215
摘要：
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II):
and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
公开/授权文献
- EP0245990A3 Antihypercholesterolemic compounds 公开/授权日：1989-07-19
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