发明公开
- 专利标题： Substituted hexahydroarylquinolizines
- 专利标题（中）： 取代基六氢芳基鸟苷。
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申请号： EP87307541.0申请日： 1987-08-26
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公开(公告)号： EP0259092A1公开(公告)日： 1988-03-09
- 发明人: Baldwin, John J. , Vacca, Joseph P. , Huff, Joel R. , Wiggins, J. Mark , De Solms, S. Jane , Young, Steven D.
- 申请人： Merck & Co., Inc.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Cole, William Gwyn
- 优先权： US901485 19860828
- 主分类号： C07D491/22
- IPC分类号： C07D491/22 ; C07D495/22 ; C07D471/22 ; A61K31/435 ; A61K31/505
摘要：
Certain substituted hexahydroarylquinolizines and pharmaceutically acceptable salts thereof are peripherally selective α₂-adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.
公开/授权文献
- EP0259092B1 Substituted hexahydroarylquinolizines 公开/授权日：1992-07-22
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