发明授权
EP0271581B1 NOVEL COMPOUNDS DC-88A AND DC-89A1 AND PROCESS FOR THEIR PREPARATION
失效
新型化合物DC-88A和DC-89A1及其制备方法
- 专利标题： NOVEL COMPOUNDS DC-88A AND DC-89A1 AND PROCESS FOR THEIR PREPARATION
- 专利标题（中）： 新型化合物DC-88A和DC-89A1及其制备方法
-
申请号： EP87902737.3申请日： 1987-04-17
-
公开(公告)号： EP0271581B1公开(公告)日： 1993-01-13
- 发明人: NAKANO, Hirofumi , TAKAHASHI, Isami , ICHIMURA, Michio , KAWAMOTO, Isao , ASANO, Kozo , TOMITA, Fusao , SANO, Hiroshi , YASUZAWA, Toru , MORIMOTO, Makoto , FUJIMOTO, Kazuhisa
- 申请人： Kyowa Hakko Kogyo Co., Ltd.
- 申请人地址： 6-1, Ohtemachi 1-chome, Chiyoda-ku, Tokyo 100 JP
- 专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址： 6-1, Ohtemachi 1-chome, Chiyoda-ku, Tokyo 100 JP
- 代理机构： Rooney, Paul Blaise
- 优先权： JP89031/86 19860417; JP95649/86 19860424
- 国际公布： WO8706265 19871022
- 主分类号： C12P1/06
- IPC分类号： C12P1/06 ; C07G11/00 ; A61K35/74
摘要：
New cpds. designated DC-88A and DC-89Al are obtd. by culture of Streptomyces species, specifically S. lydicus FERM-BP 988 or S. parvullus FERM-BP 1002. DC-88A has the molecular formula C26H25N3O8, mol. wt. (by EI-MS) 507.1624, and is sol. in methanol, ethanol, acetone, chloroform, ethyl acetate, DMSO; insol. in water, hexane. The Rf on silica gel using toluene/acetone (7:3 v/v) is 0.46. DC-89Al has the molecular formula C26H26N3O8Cl, mol. wt. 543, m.pt. 157.5-58.5 deg.C; sol. in methanol, ethanol, acetone, ethyl acetate, chloroform, DMSO; insol. in water, hexane, IR, UV, 1H NMR, 13C NMR spectral data are given for both cpds.
公开/授权文献
信息查询
