发明公开
- 专利标题： New thymopentin retro-inverso analogs and fragments thereof, a process of preparation of the new compounds and the intermediates obtained therein
- 专利标题（中）： 新的三烯酚改性逆转录酶及其片段，新化合物的制备方法及其获得的中间体
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申请号： EP88103699.0申请日： 1988-03-09
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公开(公告)号： EP0282891A3公开(公告)日： 1990-05-23
- 发明人: Sisto, Alessandro , Verdini, Antonio Silvio
- 申请人： ENIRICERCHE S.p.A. , SCLAVO S.p.A.
- 申请人地址： Corso Venezia 16 I-20121 Milan IT
- 专利权人： ENIRICERCHE S.p.A.,SCLAVO S.p.A.
- 当前专利权人： ENIRICERCHE S.p.A.,SCLAVO S.p.A.
- 当前专利权人地址： Corso Venezia 16 I-20121 Milan IT
- 代理机构： Gervasi, Gemma, Dr.
- 优先权： IT1976387 19870319
- 主分类号： C07K5/02
- IPC分类号： C07K5/02 ; C07K7/02
摘要：
New retro-inverso analogs of thymopentin (TP5) and of its tripeptide fragment (TP5¹⁻³) of general formula (I)
are described wherein R is hydrogen or an acyl radical, and R¹ is -OR² or
wherein R² is hydrogen or a hydrocarbyl radical, and the corresponding pharmaceutically acceptable acid- or base-addition salts. The new compounds are enzyme-resistant immunomodulatory peptides.
are described wherein R is hydrogen or an acyl radical, and R¹ is -OR² or
wherein R² is hydrogen or a hydrocarbyl radical, and the corresponding pharmaceutically acceptable acid- or base-addition salts. The new compounds are enzyme-resistant immunomodulatory peptides.
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