发明公开
EP0304986A2 The use of certain Calcium-Citrate-Malate for the manufacture of a medicament for the treatment of osteoporosis
失效
某些柠檬酸钙的使用苹果酸盐,一种制备用于治疗骨质疏松症的药物制剂。
- 专利标题: The use of certain Calcium-Citrate-Malate for the manufacture of a medicament for the treatment of osteoporosis
- 专利标题(中): 某些柠檬酸钙的使用苹果酸盐,一种制备用于治疗骨质疏松症的药物制剂。
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申请号: EP88201733.8申请日: 1988-08-15
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公开(公告)号: EP0304986A2公开(公告)日: 1989-03-01
- 发明人: Kochanowski, Barbara Ann
- 申请人: Norwich Eaton Pharmaceuticals, Inc.
- 申请人地址: 17 Eaton Avenue Norwich New York 13815 US
- 专利权人: Norwich Eaton Pharmaceuticals, Inc.
- 当前专利权人: Norwich Eaton Pharmaceuticals, Inc.
- 当前专利权人地址: 17 Eaton Avenue Norwich New York 13815 US
- 代理机构: Brooks, Maxim Courtney
- 优先权: US91006 19870828
- 主分类号: A61K31/19
- IPC分类号: A61K31/19 ; A23L1/29 ; A23L2/26
摘要:
Methods for building bone in a human or other animal subject, comprising administering to said subject a safe and effective amount of calcium citrate malate. The calcium citrate malate is preferably administered for at least about three months. A preferred method of the invention is for the treatment of osteoporosis. The calcium citrate malate comprises a complex of a mixture of calcium salts having a ratio of moles citrate to moles malate of from about 1:0.16 to about 1:13.5. The calcium citrate malate is preferably administered in an oral dosage form, containing pharmaceutically-acceptable carriers and excipients.
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