发明公开
- 专利标题: Substituted cycloalkanols
- 专利标题(中): 取代的环状醇
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申请号: EP88308565.6申请日: 1988-09-16
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公开(公告)号: EP0310268A3公开(公告)日: 1990-05-23
- 发明人: Husbands, George Edward Morris , Stack, Gary Paul
- 申请人: AMERICAN HOME PRODUCTS CORPORATION
- 申请人地址: Five Giralda Farms Madison, New Jersey 07940-0874 US
- 专利权人: AMERICAN HOME PRODUCTS CORPORATION
- 当前专利权人: AMERICAN HOME PRODUCTS CORPORATION
- 当前专利权人地址: Five Giralda Farms Madison, New Jersey 07940-0874 US
- 代理机构: Brown, Keith John Symons
- 优先权: US102695 19870930
- 主分类号: C07D295/08
- IPC分类号: C07D295/08 ; C07D239/42 ; C07D241/20 ; A61K31/495 ; A61K31/505
摘要:
Compounds of the formula:
in which m is one of the integers 1,2 or 3; n is one of the integers 0,1 or 2; o is one of the integers 0,1 or 2; R₁ and R₂ are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, trifluoromethyl, halo, or, when taken together, 3,4-methylenedioxy; R₃ is alkyl,
where R₄ and R₅ are, independently, hydrogen, hydroxy;l, alkyl, alkoxy, alkanoyloxy, halo or trifluoromethyl; and R₆ is hydrogen or halo; or a pharmaceutically acceptable salt thereof, are useful in treatment of psychiatric disorders.
in which m is one of the integers 1,2 or 3; n is one of the integers 0,1 or 2; o is one of the integers 0,1 or 2; R₁ and R₂ are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, trifluoromethyl, halo, or, when taken together, 3,4-methylenedioxy; R₃ is alkyl,
where R₄ and R₅ are, independently, hydrogen, hydroxy;l, alkyl, alkoxy, alkanoyloxy, halo or trifluoromethyl; and R₆ is hydrogen or halo; or a pharmaceutically acceptable salt thereof, are useful in treatment of psychiatric disorders.
公开/授权文献
- EP0310268B1 Substituted cycloalkanols 公开/授权日:1994-02-02
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