发明公开
EP0324402A1 Water-soluble salts of (+)2-(4-fluorophenyl)-alpha-methyl-5-benzoxazole acetic acid and their preparation process
失效
WasserlöslicheSalze der（+）2-（4-氟苯基）-α-甲基-5-苯并恶唑并硫醚和Herstellung。
- 专利标题： Water-soluble salts of (+)2-(4-fluorophenyl)-alpha-methyl-5-benzoxazole acetic acid and their preparation process
- 专利标题（中）： WasserlöslicheSalze der（+）2-（4-氟苯基）-α-甲基-5-苯并恶唑并硫醚和Herstellung。
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申请号： EP89100245.3申请日： 1989-01-09
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公开(公告)号： EP0324402A1公开(公告)日： 1989-07-19
- 发明人: Furlan, Diego
- 申请人： EURORESEARCH S.r.L.
- 申请人地址： Via Chiaravalle, 11 I-20122 Milano IT
- 专利权人： EURORESEARCH S.r.L.
- 当前专利权人： EURORESEARCH S.r.L.
- 当前专利权人地址： Via Chiaravalle, 11 I-20122 Milano IT
- 代理机构： Gervasi, Gemma, Dr.
- 优先权： IT1905788 19880113
- 主分类号： C07D263/56
- IPC分类号： C07D263/56 ; C07C229/26 ; A61K31/42
摘要：
Water-soluble salts of (+)2-(4-fluorophenyl)-alpha-methyl-5-benzoxazole acetic acid with DL-lysine, D-lysine or L-lysine, suitable for the preparation of medicinal specialities such as syrups, creams, suppositories, aqueous solutions for personal hygiene etc, and their preparation process.
Said salts are obtained by suspending said acid in an organic solvent soluble or partly soluble in water, adding an equivalent quatity of said lysine and crystallizing the salt obtained.
Said salts are obtained by suspending said acid in an organic solvent soluble or partly soluble in water, adding an equivalent quatity of said lysine and crystallizing the salt obtained.
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