我<图像>式的新的大环化合物，其中，在9,10-位中的虚线任选是指饱和键或双键，并且R是氢，甲基或某些酰基，和R0是氢，卤素，叠氮基，巯基，羟基或 -OY，其中下其它基团，Y表示醚基，甲硅烷基，磺酰基，糖残基或（硫代）酰基，其中R是甲基，当存在双键时在9,10-位置，具有杀微生物性质 控制植物微生物。 它们可以用于防治植物病害的常规制剂中使用。

New macrocyclic compounds of formula I wherein the dotted line in 9,10-position either a saturated bond or a double bond, and
R is hydrogen, methyl or certain acyl group, and
R₀ is hydrogen, halogen, azido, thiol, hydroxy or -OY, wherein Y represents at other residues one ether group, a silyl group, a sulfonyl group, a sugar residue or a (thio) acyl group, where R is methyl, when, in 9 10-position there is a double bond,
have microbicidal properties for controlling phytopathogenic microorganisms. They can be used in a conventional formulation for controlling plant diseases.