发明公开
- 专利标题： Conjugated gamma-hydroxybutenolide compounds and antiulcer agents containing the same as an effective ingredient
- 专利标题（中）： 结合的羟乙基羟基胆固醇化合物和含有相同成分的抗菌剂
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申请号： EP90117097.7申请日： 1990-09-05
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公开(公告)号： EP0418655A3公开(公告)日： 1991-12-18
- 发明人: Tamai, Yoshin , Torihara, Masahiro , Kido, Yoichi , Yamahara, Johji
- 申请人： KURARAY CO., LTD.
- 申请人地址： 1621 Sakazu Kurashiki-City JP
- 专利权人： KURARAY CO., LTD.
- 当前专利权人： KURARAY CO., LTD.
- 当前专利权人地址： 1621 Sakazu Kurashiki-City JP
- 代理机构： Müller-Boré & Partner Patentanwälte
- 优先权： JP245754/89 19890920
- 主分类号： C07D307/60
- IPC分类号： C07D307/60 ; C07D405/10 ; C07D409/06 ; A61K31/365 ; A61K31/38 ; A61K31/44
摘要：
The present invention provides conjugated γ -hydroxybutenolide compounds represented by the general formula:
wherein R represents, when n is 1, furyl groups, thienyl groups or naphthyl groups, unsubstituted or substituted with alkyl group or alkoxy group; phenyl groups substituted with dialkylamino group, acyl group or pyridinyl group; or
wherein m is 0, 1, 2 or 3:
when n is 2 or 3, phenyl groups unsubstituted or substituted with alkyl group or alkoxy group; and antiulcer agents comprising an aforementioned conjugated γ -hydroxybutenolide compound as an active ingredient.
wherein R represents, when n is 1, furyl groups, thienyl groups or naphthyl groups, unsubstituted or substituted with alkyl group or alkoxy group; phenyl groups substituted with dialkylamino group, acyl group or pyridinyl group; or
wherein m is 0, 1, 2 or 3:
when n is 2 or 3, phenyl groups unsubstituted or substituted with alkyl group or alkoxy group; and antiulcer agents comprising an aforementioned conjugated γ -hydroxybutenolide compound as an active ingredient.
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