发明公开
EP0425828A2 Facteur thymique sérique for prevention and remedy of disorders of decrease in the number of blood corpuscles
失效
“Facteur thymiquesérique”预防和治疗与血细胞的数目的减少相关的疾病。
- 专利标题: Facteur thymique sérique for prevention and remedy of disorders of decrease in the number of blood corpuscles
- 专利标题(中): “Facteur thymiquesérique”预防和治疗与血细胞的数目的减少相关的疾病。
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申请号: EP90118901.9申请日: 1990-10-03
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公开(公告)号: EP0425828A2公开(公告)日: 1991-05-08
- 发明人: Awaya, Akira , Kobayashi, Hisashi , Abe, Hayao
- 申请人: MITSUI TOATSU CHEMICALS, Inc.
- 申请人地址: 2-5 Kasumigaseki 3-chome Chiyoda-Ku Tokyo 100 JP
- 专利权人: MITSUI TOATSU CHEMICALS, Inc.
- 当前专利权人: MITSUI TOATSU CHEMICALS, Inc.
- 当前专利权人地址: 2-5 Kasumigaseki 3-chome Chiyoda-Ku Tokyo 100 JP
- 代理机构: VOSSIUS & PARTNER
- 优先权: JP257729/89 19891004
- 主分类号: A61K38/08
- IPC分类号: A61K38/08 ; A61K38/32
摘要:
A medicament for prevention and remedy of disorders of decrease in the number of blood corpuscles such as leukocytes, reticuloctyes and thrombocytes (blood platelets) and the use of this medicament are disclosed. The medicament contains as an effective ingredient thereof a nonapeptide having the following amino acid sequence: pGlu-Ala-Lys-Ser-Gin-Gly-Gly-Ser-Asn or an ester or an amide at the carboxyl group of the C-terminus of the asparagine or a pharmacologically acceptable salt thereof or a derivative thereof combined with a metal. This medicament is utterly non-toxic to human and animals and effective for prevention and remedy of disorders of decrease in the number of blood corpuscles such as leucocytes caused by administration of chemotherapeutics agents such as anti-cancer agents or accompanied by cancer or viral diseases.
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