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EP0429403A2 Ester of L-carnitine with gamma-hydroxybutyric acid and pharmaceutical compositions containing it for inhibiting neuronal degeneration and for the treatment of coma 失效
L-肉碱与γ-羟丁酸和含有这些用于抑制神经元变性和彗差的治疗药物组合物的酯。

Ester of L-carnitine with gamma-hydroxybutyric acid and pharmaceutical compositions containing it for inhibiting neuronal degeneration and for the treatment of coma
摘要:
The L-carnitine ester with gamma-hydroxybutyric acid and its pharmacologically accceptable salts of formula (I)
wherein X⁻ is the anion of a pharmacologically acceptable salt, e.g. chloride, bromide, orotate, acid aspartate, acid citrate, acid phosphate, acid fumarate, lactate, acid maleate, acid oxalate, acid sulfate and glucosephosphate are active in inhibiting neuronal degeneration (as it occurs in Alzheimer's senile dementia and Parkinson's disease) and in the treatment of coma.
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