发明公开
EP0436334A2 3-Aminopiperidine derivatives and related nitrogen containing heterocycles
失效
3-Aminopiperidinderivate und verwandte Nitrogen-enthaltende Heterozyklen。
- 专利标题： 3-Aminopiperidine derivatives and related nitrogen containing heterocycles
- 专利标题（中）： 3-Aminopiperidinderivate und verwandte Nitrogen-enthaltende Heterozyklen。
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申请号： EP90313680.2申请日： 1990-12-14
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公开(公告)号： EP0436334A2公开(公告)日： 1991-07-10
- 发明人: Desai, Manoj C. , Rosen, Terry J.
- 申请人： PFIZER INC.
- 申请人地址： 235 East 42nd Street New York, N.Y. 10017 US
- 专利权人： PFIZER INC.
- 当前专利权人： PFIZER INC.
- 当前专利权人地址： 235 East 42nd Street New York, N.Y. 10017 US
- 代理机构： Moore, James William, Dr.
- 优先权： PCT/US90/00116 19900104
- 主分类号： C07D207/14
- IPC分类号： C07D207/14 ; C07D211/56 ; C07D223/12 ; C07D221/20 ; A61K31/40 ; A61K31/445 ; A61K31/55
摘要：
The present invention relates to novel 3-aminopiperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula
wherein R¹, R², R³, R⁴, R⁵, R⁶, R⁷, R⁸, Y and Z are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of the formula I.
wherein R¹, R², R³, R⁴, R⁵, R⁶, R⁷, R⁸, Y and Z are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of the formula I.
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