发明公开
- 专利标题： Thioalkylthio cephalosporin derivatives
- 专利标题（中）： 噻吗啉CEPHALOSPORIN衍生物
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申请号： EP91306442.4申请日： 1991-07-16
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公开(公告)号： EP0467647A3公开(公告)日： 1992-08-12
- 发明人: Kubota, Tadatoshi , Kume, Masaharu
- 申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
- 申请人地址： 1-8, Doshomachi 3-chome, Chuo-ku Osaka 541 JP
- 专利权人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
- 当前专利权人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
- 当前专利权人地址： 1-8, Doshomachi 3-chome, Chuo-ku Osaka 541 JP
- 代理机构： Hardisty, David Robert
- 优先权： JP191889/90 19900719; JP289772/90 19901025; JP319578/90 19901121; JP147357/91 19910619
- 主分类号： C07D501/59
- IPC分类号： C07D501/59 ; A61K31/545
摘要：
A novel thioalkylthio cephalosporin antibiotic compound of formula I :
wherein Acyl is C 1 - C 12 acyl ; Het is optionally substituted monocyclic heteroaromatic group containing one or more hetero atoms ; R 1 is a single bond or C 1 - C 4 alkylene ; R 2 is a straight or branched C 1 - C 4 alkylene ; X is a sulfur atom or sulfoxide group ; and Y is a hydrogen atom or methoxy group, or a pharmaceutically acceptable salt or an amino-, carboxy- and/or hydroxy-protected derivative thereof, a formulation containing the same and a method for treating bacterial infections.
wherein Acyl is C 1 - C 12 acyl ; Het is optionally substituted monocyclic heteroaromatic group containing one or more hetero atoms ; R 1 is a single bond or C 1 - C 4 alkylene ; R 2 is a straight or branched C 1 - C 4 alkylene ; X is a sulfur atom or sulfoxide group ; and Y is a hydrogen atom or methoxy group, or a pharmaceutically acceptable salt or an amino-, carboxy- and/or hydroxy-protected derivative thereof, a formulation containing the same and a method for treating bacterial infections.
公开/授权文献
- EP0467647B1 Thioalkylthio cephalosporin derivatives 公开/授权日：1994-08-17
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