发明授权
- 专利标题: NEUE PROTEINE MIT TNF-HEMMENDER WIRKUNG UND IHRE HERSTELLUNG
- 专利标题(英): Novel tnf-inhibit proteins and their preparation
- 专利标题(中): 与TNF-锁作用和生产新的蛋白质。
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申请号: EP90906924.7申请日: 1990-05-04
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公开(公告)号: EP0471701B1公开(公告)日: 1994-10-19
- 发明人: LEMAIRE, Hans-Georg , HILLEN, Heinz , MOELLER, Achim , DAUM, Lothar , DOERPER, Thomas , SUBKOWSKI, Thomas
- 申请人: BASF Aktiengesellschaft
- 申请人地址: Carl-Bosch-Strasse 38 67063 Ludwigshafen DE
- 专利权人: BASF Aktiengesellschaft
- 当前专利权人: BASF Aktiengesellschaft
- 当前专利权人地址: Carl-Bosch-Strasse 38 67063 Ludwigshafen DE
- 优先权: DE3915072 19890509; DE3922089 19890705
- 国际公布: WO9013575 19901115
- 主分类号: C07K15/14
- IPC分类号: C07K15/14 ; A61K35/12
摘要:
Novel proteins have a molecular weight of approximately 42.000 daltons and the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu on their terminal N, where X denotes a hydrogen atom, a phenylalanine (Phe) residue or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe. These proteins have a therapeutic effect.
公开/授权文献
- EP0471701B2 NEUE PROTEINE MIT TNF-HEMMENDER WIRKUNG UND IHRE HERSTELLUNG 公开/授权日:2007-03-07
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