发明公开
EP0480715A1 Intermediates for preparing 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents
失效
用于制备2-（取代的二苯并呋喃基二苯并噻吩和）中间体-carbapenems用作抗菌剂。
- 专利标题： Intermediates for preparing 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents
- 专利标题（中）： 用于制备2-（取代的二苯并呋喃基二苯并噻吩和）中间体-carbapenems用作抗菌剂。
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申请号： EP91309303.5申请日： 1991-10-09
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公开(公告)号： EP0480715A1公开(公告)日： 1992-04-15
- 发明人: Dininno, Frank P. , Greenlee, Mark L. , Salzmann, Thomas N.
- 申请人： MERCK & CO. INC.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： MERCK & CO. INC.
- 当前专利权人： MERCK & CO. INC.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Thompson, John Dr.
- 优先权： US596145 19901011
- 主分类号： C07D477/00
- IPC分类号： C07D477/00
摘要：
Carbapenem intermediates having the formula:
where Z is
M is a removable protecting group for carboxy and P′ is a removable protecting group for hydroxy, are useful intermediates for preparing antibacterial agents, especially with respect to activity against methicillin resistant Staphylococcus aureus (MRSA).
where Z is
M is a removable protecting group for carboxy and P′ is a removable protecting group for hydroxy, are useful intermediates for preparing antibacterial agents, especially with respect to activity against methicillin resistant Staphylococcus aureus (MRSA).
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