An apparatus for producing and automatically injecting H 2 15 0, comprises : a target box (1) adapted to be irradiated with a deuteron beam ; a gas supplying device (21-26) for supplying a hydrogen gas and a nitrogen gas as raw-material gases to the target box; a radioactive-isotope conveying pipe (4) connecting the target box; and a vacuum pump (3) for maintaining the interior of the target box and the interior of the radioactive-isotope conveying pipe in a vacuum state. In addition, the apparatus further comprises an injection-fluid producing device (5) and an automatic injection (6) device, wherein the target box, the injection-fluid producing device and the automatic injection device are fluidly connected with one another.