发明公开
- 专利标题： Verfahren zur Herstellung einer in 3-Stellung fluorierten aromatischen Verbindung
- 专利标题（中）： 取代基氟苯。
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申请号： EP92303617.2申请日： 1992-04-22
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公开(公告)号： EP0512715A2公开(公告)日： 1992-11-11
- 发明人: Moilliet, John Stewart , Chambers, Richard Dickinson , Rock, Michael Harold
- 申请人： ZENECA LIMITED
- 申请人地址： 15 Stanhope Gate London W1Y 6LN GB
- 专利权人： ZENECA LIMITED
- 当前专利权人： ZENECA LIMITED
- 当前专利权人地址： 15 Stanhope Gate London W1Y 6LN GB
- 代理机构： Giles, David Eric
- 优先权： GB9110181 19910510
- 主分类号： C07C17/12
- IPC分类号： C07C17/12 ; C07C309/86 ; C07C63/10 ; C07C49/327 ; C07C255/50 ; C07C63/70 ; C07B39/00
摘要：
Introduction of a fluoro substituent into an aromatic ring adjacent an electron donating group is difficult producing mixed isomers and low yields of desired products.
A process for the introduction of a fluoro substituent into substantially in an adjacent position to an electron-donating group into an aromatic compound in high yield is disclosed.
The fluoroaromatic compounds are useful as synthetic intermediates for example in the manufacture of agrochemicals, pharmaceuticals and dyestuffs.
A process for the introduction of a fluoro substituent into substantially in an adjacent position to an electron-donating group into an aromatic compound in high yield is disclosed.
The fluoroaromatic compounds are useful as synthetic intermediates for example in the manufacture of agrochemicals, pharmaceuticals and dyestuffs.
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