发明公开
- 专利标题： Cyclic renin inhibitors
- 专利标题（中）： 环状肾素抑制剂
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申请号： EP92305379.7申请日： 1992-06-11
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公开(公告)号： EP0518672A3公开(公告)日： 1993-08-11
- 发明人: Dhanoa, Daljit S. , Patchett, Arthur A. , Greenlee, William J. , Parsons, William H. , Halgren, Thomas A. , Weber, Ann E. , Yang, Lihu
- 申请人： MERCK & CO. INC.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： MERCK & CO. INC.
- 当前专利权人： MERCK & CO. INC.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Thompson, John Dr.
- 优先权： US714114 19910611
- 主分类号： C07K5/02
- IPC分类号： C07K5/02 ; C07K5/06 ; C07D271/00 ; C07D413/12 ; C07D273/00 ; C07D245/02 ; C07D323/00 ; C07D291/02 ; C07D419/12 ; A61K31/00 ; A61K37/64
摘要：
Compounds of the formula :
are disclosed. These compounds inhibit the angiotensinogen-cleaving action of the natural proteolytic enzyme, renin, and are useful in treating, preventing or managing renin-associated hypertension, hyperaldosteronism, congestive heart failure, and glaucoma.
are disclosed. These compounds inhibit the angiotensinogen-cleaving action of the natural proteolytic enzyme, renin, and are useful in treating, preventing or managing renin-associated hypertension, hyperaldosteronism, congestive heart failure, and glaucoma.
公开/授权文献
- EP0518672A2 Cyclic renin inhibitors 公开/授权日：1992-12-16
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