发明公开
EP0528343A2 New process for the production of cephalosporines and novel intermediates in this process 失效
Verfahren zur Herstellung von Cephalosporinen und Zwischenverbindungen in diesem Verfahren。

New process for the production of cephalosporines and novel intermediates in this process
摘要:
The invention relates to a new economical and simple process, using a new intermediate compound, for the production of 3'-substituted 7-amino-3-propenyl-4-cephem-carboxylic acid derivatives of formula

wherein R is hydrogen, a negative charge or a silyl protecting group, R o is hydrogen or methoxy, R₁ is hydrogen or a silyl protecting group and X is the radical of a nucleophile, and their acid addition salts.
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