发明公开
EP0530994A1 Quinazoline derivatives as inhibitors of HIV reverse transcriptase
失效
Chinazolinderivate als Inhibitoren von reversen Transcriptasen von HIV。
- 专利标题： Quinazoline derivatives as inhibitors of HIV reverse transcriptase
- 专利标题（中）： Chinazolinderivate als Inhibitoren von reversen Transcriptasen von HIV。
-
申请号： EP92307398.5申请日： 1992-08-12
-
公开(公告)号： EP0530994A1公开(公告)日： 1993-03-10
- 发明人: Britcher, Susan F. , Lumma, William C., Jr. , Goldman, Mark E. , Lyle, Terry A. , Huff, Joel R. , Payne, Linda S. , Quesada, Martha L. , Young, Steven D. , Sanders, William M. , Sanderson, Philip E. , Tucker, Thomas J.
- 申请人： MERCK & CO. INC.
- 申请人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 专利权人： MERCK & CO. INC.
- 当前专利权人： MERCK & CO. INC.
- 当前专利权人地址： 126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
- 代理机构： Barrett-Major, Julie Diane
- 优先权： US746445 19910816; US880121 19920507
- 主分类号： C07D239/80
- IPC分类号： C07D239/80 ; C07D239/82 ; C07D487/04 ; C07D498/04 ; C07D405/04 ; A61K31/505
摘要：
Compounds having a quinazolin-2-(thi)one nucleus are described. These compounds are useful in the inhibition of HIV reverse transcriptase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
信息查询
