发明公开
EP0537802A3 N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia
失效
N-亚乙基吡咯烷酮和N-乙酰胆碱，其制备方法及其用于预防和/或治疗亚眠的用途
- 专利标题： N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia
- 专利标题（中）： N-亚乙基吡咯烷酮和N-乙酰胆碱，其制备方法及其用于预防和/或治疗亚眠的用途
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申请号： EP92121896.2申请日： 1989-04-06
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公开(公告)号： EP0537802A3公开(公告)日： 1993-06-02
- 发明人: Toda, Masaaki , Ohuchida, Shuichi, Shinbayashidanchi 19-103 , Ohno, Hiroyuki
- 申请人： ONO PHARMACEUTICAL CO., LTD.
- 申请人地址： 1-5, Doshomachi 2-chome Chuo-ku Osaka-shi Osaka JP
- 专利权人： ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人： ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 1-5, Doshomachi 2-chome Chuo-ku Osaka-shi Osaka JP
- 代理机构： Henkel, Feiler, Hänzel & Partner
- 优先权： JP85288/88 19880408
- 主分类号： C07D207/08
- IPC分类号： C07D207/08 ; C07D277/04 ; C07D277/06 ; C07D401/06 ; C07D405/04 ; A61K31/40
摘要：
N-Acyl Pyrrozidines and N-Acyl Thiazolidines of the general formula:
wherein, Z represents a methylene group or a sulfur atom, their non-toxic salts or hydrates. The compounds possess an inhibitory activity on propyl endopeptidase, and therefore are usefull for the prevention and/or treatment of amnesia.
wherein, Z represents a methylene group or a sulfur atom, their non-toxic salts or hydrates. The compounds possess an inhibitory activity on propyl endopeptidase, and therefore are usefull for the prevention and/or treatment of amnesia.
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