发明公开
EP0559625A3 Esters of L-carnitine and acyl L-carnitine endowed with muscle relaxant activityselective on gastrointestinal tract and pharmaceutical compositions containing same
失效
含有肌酸激酶活性选择性的L-卡尼汀和ACYL L CARNITINE在胃肠道触剂和含有其的药物组合物中的作用
- 专利标题： Esters of L-carnitine and acyl L-carnitine endowed with muscle relaxant activityselective on gastrointestinal tract and pharmaceutical compositions containing same
- 专利标题（中）： 含有肌酸激酶活性选择性的L-卡尼汀和ACYL L CARNITINE在胃肠道触剂和含有其的药物组合物中的作用
-
申请号： EP93830083.7申请日： 1993-03-01
-
公开(公告)号： EP0559625A3公开(公告)日： 1993-12-01
- 发明人: Scafetta, Nazareno , Santaniello, Mosé , Tinti, Maria Ornella , Misiti, Domenico , Stasi, Maria Antonietta , Vesci, Loredana , Corsico, Nerima
- 申请人： Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
- 申请人地址： Viale Shakespeare, 47 I-00144 Roma IT
- 专利权人： Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
- 当前专利权人： Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
- 当前专利权人地址： Viale Shakespeare, 47 I-00144 Roma IT
- 代理机构： Cavattoni, Fabio
- 优先权： ITRM920138 19920302
- 主分类号： C07C229/22
- IPC分类号： C07C229/22 ; A61K31/22
摘要：
Esters of L-carnitine and acyl L-carnitine of formula (I):
wherein
R is hydrogen or is a straight or branched, saturated or unsaturated acyl group having 2 to 26 carbon atoms; R 1 is a straight or branched, saturated or unsaturated alkyl group having 4 to 26 carbon atoms; and X- is the anion of a pharmacologically acceptable acid
are endowed with potent muscle relaxant activity selective on the gastrointestinal tract and are therefore therapeutically useful for treating e.g. adaptive colitis syndromes.
wherein
R is hydrogen or is a straight or branched, saturated or unsaturated acyl group having 2 to 26 carbon atoms; R 1 is a straight or branched, saturated or unsaturated alkyl group having 4 to 26 carbon atoms; and X- is the anion of a pharmacologically acceptable acid
are endowed with potent muscle relaxant activity selective on the gastrointestinal tract and are therefore therapeutically useful for treating e.g. adaptive colitis syndromes.
公开/授权文献
信息查询
