发明授权
- 专利标题： REDIRECTION OF CELLULAR IMMUNITY BY RECEPTOR CHIMERAS
- 专利标题（中）： 细胞免疫通过受体嵌合体CHANGE
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申请号： EP92907958.0申请日： 1992-03-06
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公开(公告)号： EP0574512B1公开(公告)日： 2003-02-05
- 发明人: SEED, Brian , ROMEO, Charles , KOLANUS, Waldemar
- 申请人： THE GENERAL HOSPITAL CORPORATION
- 申请人地址： Office of Technology Affairs, Thirteenth Street, Building 149, Suite 1101 Charlestown, MA 02129 US
- 专利权人： THE GENERAL HOSPITAL CORPORATION
- 当前专利权人： THE GENERAL HOSPITAL CORPORATION
- 当前专利权人地址： Office of Technology Affairs, Thirteenth Street, Building 149, Suite 1101 Charlestown, MA 02129 US
- 代理机构： Fischer, Hans-Jürgen, Dr.
- 优先权： US665961 19910307
- 国际公布： WO92015322 19920917
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07K17/00 ; A61P35/00
摘要：
Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated cell. Also disclosed are cells which express the chimeric receptors and DNA encoding the chimeric receptors.
公开/授权文献
- EP0574512A1 REDIRECTION OF CELLULAR IMMUNITY BY RECEPTOR CHIMERAS 公开/授权日：1993-12-22
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