发明公开
EP0626859A1 INHIBITION OF NITRIC OXIDE-MEDIATED HYPOTENSION AND SEPTIC SHOCK WITH IRON-CONTAINING HEMOPROTEIN
失效
抑制由一氧化氮介导性低血压与血红素蛋白感染性休克。
- 专利标题: INHIBITION OF NITRIC OXIDE-MEDIATED HYPOTENSION AND SEPTIC SHOCK WITH IRON-CONTAINING HEMOPROTEIN
- 专利标题(中): 抑制由一氧化氮介导性低血压与血红素蛋白感染性休克。
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申请号: EP93905917.0申请日: 1993-02-16
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公开(公告)号: EP0626859A1公开(公告)日: 1994-12-07
- 发明人: KILBOURN, Robert, G. , DE ANGELO, Joseph , BONAVENTURA, Joseph
- 申请人: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM , DUKE UNIVERSITY , APEX BIOSCIENCE, INC.
- 申请人地址: Office of General Council, 201 West 7th Street Austin, Texas 78701 US
- 专利权人: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM,DUKE UNIVERSITY,APEX BIOSCIENCE, INC.
- 当前专利权人: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM,DUKE UNIVERSITY,APEX BIOSCIENCE, INC.
- 当前专利权人地址: Office of General Council, 201 West 7th Street Austin, Texas 78701 US
- 代理机构: Allard, Susan Joyce, et al
- 优先权: US19920838603 19920219
- 国际公布: WO1993016721 19930902
- 主分类号: A61K38
- IPC分类号: A61K38 ; A61P9
摘要:
The invention is directed to a method for the prophylaxis or treatment of an animal for deleterious physiological effects such as systemic hypotension caused by nitric oxide production induced by a biological response modifier. Examples of such biological response modifiers include but are not limited to a cytokine and an endotoxin. The invention is also directed to a method for the treatment of septic shock.
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