发明授权
EP0635012B1 UNBRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE
失效
非桥接的二芳基 - 甲醇衍生物,组合物及其
- 专利标题: UNBRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE
- 专利标题(中): 非桥接的二芳基 - 甲醇衍生物,组合物及其
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申请号: EP93908326.7申请日: 1993-03-22
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公开(公告)号: EP0635012B1公开(公告)日: 1996-07-10
- 发明人: FRIARY, Richard , PIWINSKI, John, J. , WONG, Jesse, K.
- 申请人: SCHERING CORPORATION
- 申请人地址: 2000 Galloping Hill Road Kenilworth New Jersey 07033 US
- 专利权人: SCHERING CORPORATION
- 当前专利权人: SCHERING CORPORATION
- 当前专利权人地址: 2000 Galloping Hill Road Kenilworth New Jersey 07033 US
- 代理机构: Ritter, Stephen David
- 优先权: US858919 19920327
- 国际公布: WO9320063 19931014
- 主分类号: C07D401/06
- IPC分类号: C07D401/06 ; A61K31/44 ; C07D401/14 ; C07D417/14 ; C07D409/14
摘要:
Disclosed is a compound of Formula (1.0) or a pharmaceutically acceptable salt or solvate thereof, wherein AR1 represents (a), AR2 represents (b) or a five-membered heterocyclic aromatic group selected from the group consisting of Formulas (I to XII), wherein the substitutable carbon atoms of the five-membered heterocyclic group can optionally be substituted with a group R1. Also disclosed are pharmaceutical compositions containing compounds of Formula (1.0). Further disclosed is a method for treating asthma, allergy and inflammation by administering an anti-asthmatic, anti-allergic or anti-inflammatory, respectively, effective amount of a compound of Formula (1.0).
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