发明公开
EP0638321A1 Ipriflavone and pharmaceutical compositions and their use for bone defect substitution
失效
含有它们以及它们用于骨缺损的代用品使用依普黄酮药物组合物。
- 专利标题： Ipriflavone and pharmaceutical compositions and their use for bone defect substitution
- 专利标题（中）： 含有它们以及它们用于骨缺损的代用品使用依普黄酮药物组合物。
-
申请号： EP94111951.3申请日： 1994-08-01
-
公开(公告)号： EP0638321A1公开(公告)日： 1995-02-15
- 发明人: Prezmeczky, Dr. Làszl , Klenk, Dr. Gusztáv , Englovszky, Ms. Erzsébet , Horváth, Dr. Tibor , Miszkiewicz, Dr.Lászlo , Székács, Dr. Gábor , Lévai, Dr. Ferenc , Vitányi née Morvai, Mrs. Magdolna
- 申请人： CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT.
- 申请人地址： To utca 1-5 H-1045 Budapest IV HU
- 专利权人： CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT.
- 当前专利权人： CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT.
- 当前专利权人地址： To utca 1-5 H-1045 Budapest IV HU
- 代理机构： Patentanwälte Beetz - Timpe - Siegfried Schmitt-Fumian - Mayr
- 优先权： HU9302230 19930802
- 主分类号： A61L27/00
- IPC分类号： A61L27/00 ; A61K31/35 ; A61K33/42 ; A61K6/033 ; A61K6/00
摘要：
The invention relates to the use of Ipriflavone (7-isopropoxyisoflavone) and combinations thereof with porous hydroxylapatite and/or tricalcium phosphate for the substitution of bone defects having pathologically developed or being artificially established, as well as to compositions containing these active ingredients and their preparation.
In the combinations of the invention, the mass ratio A/B of porous hydroxylapatite and/or tricalcium phosphate (A) to Ipriflavone (B) is preferably 1:9 to 9:1 and most preferably 1:1. The components are preferably present in the form of discrete granules.
Preferably, the Ipriflavone is applied onto the surface of the porous hydroxylapatite and/or tricalcium phosphate.
The compositions of the invention lead to an accelerated bone formation.
In the combinations of the invention, the mass ratio A/B of porous hydroxylapatite and/or tricalcium phosphate (A) to Ipriflavone (B) is preferably 1:9 to 9:1 and most preferably 1:1. The components are preferably present in the form of discrete granules.
Preferably, the Ipriflavone is applied onto the surface of the porous hydroxylapatite and/or tricalcium phosphate.
The compositions of the invention lead to an accelerated bone formation.
公开/授权文献
信息查询
