发明公开
EP0638588A1 Derivatives of 6,7-Dihydroxy-4-thiaheptonic acid and their use
失效
衍生自6,7-二羟基-4-thiaheptansäureund deren Verwendung。
- 专利标题： Derivatives of 6,7-Dihydroxy-4-thiaheptonic acid and their use
- 专利标题（中）： 衍生自6,7-二羟基-4-thiaheptansäureund deren Verwendung。
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申请号： EP94111469.6申请日： 1994-07-22
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公开(公告)号： EP0638588A1公开(公告)日： 1995-02-15
- 发明人: Hida, Tsuneaki , Tanida, Seiichi , Harada, Setsuo , Yukishige, Koichi
- 申请人： TAKEDA CHEMICAL INDUSTRIES, LTD.
- 申请人地址： 3-6, Doshomachi 2-chome Chuo-ku, Osaka 541 JP
- 专利权人： TAKEDA CHEMICAL INDUSTRIES, LTD.
- 当前专利权人： TAKEDA CHEMICAL INDUSTRIES, LTD.
- 当前专利权人地址： 3-6, Doshomachi 2-chome Chuo-ku, Osaka 541 JP
- 代理机构： Casalonga, Axel
- 优先权： JP181735/93 19930722; JP6670/94 19940125
- 主分类号： C07K5/06
- IPC分类号： C07K5/06 ; C07K5/08 ; C07K5/10 ; C07K7/06
摘要：
A compound of the formula:
wherein each of R¹ and R² is hydrogen or an aliphatic acyl group, each of R³ and R⁴ is hydrogen or a protecting group, X is an amino acid sequence consisting of 1 to 10 amino acid residues which may be protected, Y is an amino acid sequence consisting of 1 to 5 amino acids residues which may be protected, bounding at a terminal carboxyl group, or a salt thereof has an activity of remarkably improving hematopoietic disorder and is useful as an immuno-stimulating agent or an agent for treating thrombocytopenia.
wherein each of R¹ and R² is hydrogen or an aliphatic acyl group, each of R³ and R⁴ is hydrogen or a protecting group, X is an amino acid sequence consisting of 1 to 10 amino acid residues which may be protected, Y is an amino acid sequence consisting of 1 to 5 amino acids residues which may be protected, bounding at a terminal carboxyl group, or a salt thereof has an activity of remarkably improving hematopoietic disorder and is useful as an immuno-stimulating agent or an agent for treating thrombocytopenia.
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