发明公开
- 专利标题: CONDENSED CARBAPENEM DERIVATIVES
- 专利标题(中): 简明碳青霉烯类。
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申请号: EP93919157.0申请日: 1993-08-25
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公开(公告)号: EP0656899A1公开(公告)日: 1995-06-14
- 发明人: CARLESSO, Roberto , HOLMAN, Stuart, Glaxo Group Research Limited , PERBONI, Alcide , ROSSI, Tino
- 申请人: GLAXO S.p.A.
- 申请人地址: Via Alessandro Fleming 2 I-37100 Verona IT
- 专利权人: GLAXO S.p.A.
- 当前专利权人: GLAXO S.p.A.
- 当前专利权人地址: Via Alessandro Fleming 2 I-37100 Verona IT
- 代理机构: Filler, Wendy Anne, et al
- 优先权: GB19920018240 19920827
- 国际公布: WO1994005666 19940317
- 主分类号: A61K31
- IPC分类号: A61K31 ; A61P31 ; C07D477
摘要:
The present invention relates to compounds of formula (I) and salts and metabolically labile esters thereof; wherein R is a 5 or 6 membered nitrogen containing heteroaryl group, which heteroaryl group optionally contains 1 or 2 additional heteroatoms selected from nitrogen, oxygen or sulphur and said heteroaryl group is linked to the alkylene chain (CH2)n via a nitrogen atom in the heteroaryl group; n is an integer from 2 to 4, to processes for their preparation and to their use as antibacterial agents.
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