发明公开
- 专利标题： ANTINEOPLASTIC HETERONAPHTHOQUINONES
- 专利标题（中）： 抗骨质疏松剂乙酰奎尼酸
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申请号： EP93924460.0申请日： 1993-11-05
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公开(公告)号： EP0659190A1公开(公告)日： 1995-06-28
- 发明人: ATTARDO, Giorgio , BREINING, Tibor , COURCHESNE, Marc , KRAUS, Jean-Louis , LAMOTHE, Serge , LAVALLEE, Jean-François , LEBEAU, Elaine , NGUYEN, Dieu , REJ, Rabindra , ST-DENIS, Yves , WANG, Wuyi , XU, Yao-Chang , BARBEAU, France 200 Boulevard DuDomaine
- 申请人： BIOCHEM PHARMA INC.
- 申请人地址： 275 Armand-Frappier Boulevard Laval, Quebec H7V 4A7 CA
- 专利权人： BIOCHEM PHARMA INC.
- 当前专利权人： BIOCHEM PHARMA INC.
- 当前专利权人地址： 275 Armand-Frappier Boulevard Laval, Quebec H7V 4A7 CA
- 代理机构： Ritter, Stephen David, et al
- 优先权： US19920973233 19921109
- 国际公布： WO1994011382 19940526
- 主分类号： C07D311
- IPC分类号： C07D311 ; C07D335 ; C07H15 ; C07H17
摘要：
Tricyclic heteronaphthoquinone derivatives, that have antineoplastic activity, are disclosed, together with processes for their synthesis. Some of these anti-neoplastics compounds have a saccharide moiety. Some members of this structurally distinct group exhibit activity against multiple drug resistant cancer cells.
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