发明公开
- 专利标题： HEPATITIS A VIRUS VACCINES
- 专利标题（中）： 甲型肝炎病毒疫苗。
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申请号： EP93921524.0申请日： 1993-09-17
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公开(公告)号： EP0666751A1公开(公告)日： 1995-08-16
- 发明人: FUNKHOUSER, Ann, W. , EMERSON, Suzanne, U. , PURCELL, Robert, H. , D'HONDT, Eric
- 申请人： SMITHKLINE BEECHAM BIOLOGICALS s.a. , THE GOVERNMENT OF THE UNITED STATES OF AMERICA c/o as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVI
- 申请人地址： 89 rue de l'Institut B-1330 Rixensart BE
- 专利权人： SMITHKLINE BEECHAM BIOLOGICALS s.a.,THE GOVERNMENT OF THE UNITED STATES OF AMERICA c/o as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVI
- 当前专利权人： SMITHKLINE BEECHAM BIOLOGICALS s.a.,THE GOVERNMENT OF THE UNITED STATES OF AMERICA c/o as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVI
- 当前专利权人地址： 89 rue de l'Institut B-1330 Rixensart BE
- 代理机构： Hale, Stephen Geoffrey
- 优先权： US19920947338 19920918
- 国际公布： WO1994006446 19940331
- 主分类号： C12N15
- IPC分类号： C12N15 ; A61K35 ; A61K39 ; A61P31 ; C07K14 ; C12N7 ; C12P21 ; C12R1
摘要：
A live hepatitis A virus adapted to growth in MRC-5 cells, which HAV is preferably characterized by suitable attenuation for effective vaccine administration to humans and animals without inactivation, methods for adapting HAV to growth in MRC-5, vaccine compositions and method of vaccinating humans against HAV infection.
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